Luvi Silverberg
November 11, 2022

How to Make Hydroxyquinoline with Grapefruit and Lemon


Hydroxyquinoline is a chemical compound that is used in medicine and cosmetics. It's made from several ingredients, including citrus fruit. This process may sound complicated, but it's actually quite simple. In this article, we'll show you how to make hydroxyquinoline at home using common ingredients like grapefruit and lemon.

Gather the ingredients.

The first step to making hydroxyquinoline is to gather your ingredients. You will need a citrus fruit, such as grapefruit or lemon; a glass jar; salt, and water.

The next step is to slice your citrus fruit into thin sheets. Then, add the salt, water and lemon juice together in a glass jar.

Peel the grapefruit with a sharp knife and remove the pith.

Peel the grapefruit with a sharp knife and remove the pith. Use a paring knife or other small serrated blade to trim away any excess flesh. Cut it into quarters and then slice each quarter in half lengthwise, following the natural curve of the fruit so that you end up with four long stripes of grapefruit. Now cut each stripe into 1/4-inch slices, discarding any seeds as you go along.

On each plate, place two slices of grapefruit alongside one another in parallel lines as shown above (the remaining slices can be stored in an airtight container for later use). Add 1/2 tablespoon lemon juice to each plate and let sit for 10 minutes before serving to allow all flavors to mingle together nicely!

Thinly slice and then mince the citrus peel.

To begin, you'll need to remove the peel from both fruits. This is a relatively easy process that requires only a sharp paring knife and a little bit of patience.

First, cut away the top and bottom of each citrus fruit so that it sits flatly on your work surface. With one hand holding the orange or grapefruit steady, use your other hand to slice off as much peel as possible with an upward motion (just like removing an apple's skin). Once done peeling all around, flip over your orange or grapefruit and repeat this process with the other side until all of its white pith has been removed in strips. Finally, trim off any remaining pieces where necessary using small cuts made at an angle towards either end—you don't want any extra hanging out there!

Next up? Mincing! Mince roughly two cups' worth of peeled citrus material into tiny cubes using either a paring knife or food processor; you don't have to be too meticulous here since we're going for flavor rather than fine pieces anyway!

Heat the minced rind, water, and salt in a saucepan over medium heat.

Heat the minced rind, water and salt in a saucepan over medium heat. Stir until the mixture boils. Remove from heat and let cool for about 5 minutes. Add the rind to your jar of choice (we used an 8-ounce mason jar) and fill with cool water up to the top of the jar without covering up any of the grapefruit peels at all. Cover with a lid or plastic wrap secured by a rubber band or hair tie if necessary (to keep fruit flies out). Leave out at room temperature for 24 hours before transferring to fridge; allow 3 days total to ferment before using as needed!

Bring the mixture to a boil and then remove from heat.

To make hydroxyquinoline with grapefruit and lemon, bring the mixture to a boil and then remove from heat. Let the mixture cool before pouring into a jar. Cover with a lid and place in a warm place for 7 days.

Put the mixture into a glass jar and place in a warm place for 7 days.

After you have let the solution sit for 7 days, it is time to filter and dry your resulting hydroxyquinoline. To do this, line a funnel with a coffee filter or cheesecloth and place the funnel on top of a large pitcher or bowl. Pour the contents of your jar into this funnel, leaving behind any solids that may be left in there. Set aside what has passed through into your pitcher/bowl and repeat until all of the mixture has been filtered.

Now comes the fun part: separating out hydroxyquinolines! Take some acetone (nail polish remover) and add about 10mls (2 tsp) to each container with liquid from your filtering process. Shake up each container well (about 15 seconds). You will notice that some liquids are now darker than others—this is because they contain more hydroxyquinolines!

You can make medicines at home using common ingredients like citrus fruit.

You can make medicines at home using common ingredients like citrus fruit. Hydroxyquinoline is a chemical compound used in medicine, often to treat infections and as a topical antiseptic.


Hydroxyquinoline is a chemical compound that has many uses, including being an anti-bacterial agent and an analgesic. It can also be used to treat various diseases, such as malaria and cancer. The process of making hydroxyquinoline at home requires some time but it's relatively easy if you have the right ingredients. The most important thing when making this medicine is to use high quality grapefruit or lemon juice because their citric acid content will help preserve the correct chemical composition during fermentation process